The Patriots have the league’s highest win total, at 11, after closing at 12½ last season, when they went 13-3.
The Eagles opened as 3½-point home favorites over the Falcons at the Westgate sports book, which posted lines on each of the 16 Week 1 games Thursday night shortly after the NFL announced its 2018 schedule.
Gronkowski, a 3-year-old colt, has won all three of his starts this year. He earned a spot in the 20-horse Derby field by virtue of leading the point standings among Europe-based horses.
Sharp bettors backed the Kings over the Golden Knights on Sunday night in Game 3 of their NHL playoff series.