Besides the strike-shortened 1987 season, this is reportedly the first time since the 1970s that two NFL teams have been favored by at least 21 points in the same week.
Ed Salmons, Westgate sportsbook vice president of risk management, said the Bulldogs are motivated to embarrass the Fighting Irish in a game between top 10 teams.
Utah is 20-8-1 against the spread on the road since 2014, and the Utes have covered their last three and four of five against Southern California.
Tennessee, a consensus 1½-point road favorite over Jacksonville, has won the last four meetings between the teams and six of the last seven.
The Cardinals have yet to win a game on the field, but the team is perfect against the spread through two weeks.
The Dolphins look like the worst team in the NFL, and might even be the worst team in Miami.
The Browns opened as 2½-point road favorites but the line shot up to 6½ after Jets quarterback Sam Darnold was ruled out with mononucleosis.
A bettor at CG Technology sportsbook cashed a $424 eight-team NFL parlay for $74,000 when the Cleveland Browns covered the 6½-point spread in a 23-3 win over the New York Jets on “Monday Night Football.”
New England is the team that America loves to hate but it also loves to bet on the Patriots, who easily covered the 18½-point spread in a 43-0 road rout of the Dolphins.
Opening and closing lines and ATS highlights for every NFL Sunday game.