The crash was reported about 7:30 p.m. Tuesday on the 1800 block of Winterwood Boulevard, near Nellis and Charleston boulevards.
Edgar Mendoza-Fernandez, 39, was booked into the Clark County Detention Center on Wednesday in connection with the crash.
Las Vegas police said a suspected DUI driver first hit a parked vehicle before jumping the curb, striking a woman on the sidewalk and finally crashing into a house.
The driver tried to flee from the scene, police said, but residentsheld him down until police arrived.
Mendoza-Fernandez was arrested on one charge each of failure to maintain lane, driving without a valid license and driving under the influence resulting in substantial bodily harm.