Another unhelpful Reid remark?

When Democrats have needed to reach out for Republican support in the U.S. Senate, the first numbers on their speed dial have belonged to Maine moderate Sens. Olympia Snowe and Susan Collins.

But that relationship may have been complicated a bit, at least with Snowe, following another off-the-cuff comment from Sen. Harry Reid.

The Senate majority leader is quoted in an upcoming New York Times Magazine story taking a shot at Snowe, who had spoken with the White House about the health care bill last year but eventually voted against it. 

Reid told reporter Adam Nagourney it had been a "waste of time" for the White House to negotiate with Snowe, because "she had no intention of ever working anything out."

Now, with Democrats needing at least one Republican vote on controversial bills to offset the loss of their Senate seat in Massachusetts,  Snowe isn't sounding happy about working with Dems, Politico reports.

“I don’t even know why he would be critical,” Snowe said of Reid, according to the report. "No good deed goes unpunished, they say."

This was the same New York Times Magazine article in which Reid was quoted saying Sen. Joseph Lieberman "double-crossed me" on the health care bill. Reid later moved to smooth that one over.