The first phase of the three-year project will begin Wednesday on a stretch of both sides of the Las Vegas Strip running between Resorts World Drive and Spring Mountain Road.
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University Center Drive runs out of McCarran International Airport, past the Thomas & Mack Center and the UNLV campus, winding down to Desert Inn Road.
The proposed project would improve traffic flow to and from Allegiant Stadium, T-Mobile Arena and the Strip Cooridor, add high occupancy vehicle ramps at the Harmon Avenue overpass.
Making the routes commuters drive more aesthetically pleasing is a goal of the state Department of Transportation as it completes improvement projects on state maintained roads.
The Lamb Boulevard on-and-offramps of the northern 215 Beltway will close to traffic at 9 p.m. Sunday.