Las Vegas expert takes issue with new study of dementia interventions

Updated June 22, 2017 - 10:56 pm

A world-renowned Las Vegas expert on dementia is taking issue with a major study released Thursday by the National Academy of Sciences, saying the researchers set the bar too high in searching for evidence that blood pressure management, increased physical activity and cognitive training can slow or prevent the onset of the brain disorder.

The study by the National Academies of Science, Engineering and Medicine found “encouraging” but inconclusive evidence that the three actions might help stave off dementia, including its most common form, Alzheimer’s disease. But without proof, the government should not begin a public health campaign pushing the strategies for aging brain health, it said.

But Dr. Jeffrey Cummings, medical director of the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas, said the researchers erred in expecting results from lifestyle interventions such as physical and mental exercise to be as clear as those from controlled trials of drugs, where one group gets a placebo and the other gets the drug being tested.

‘The evidence is … strong’

“The evidence is, in fact, strong enough,” he said. “We’ve looked at Alzheimer’s internationally, and experts around the world have come to the same conclusion we did — there is enough encouraging data to get people to be more involved in their general health.”

The study did not discount the benefits of managing blood pressure, increasing physical activity and cognitive training — everything from the learning of foreign languages to the working of crossword puzzles – but said evidence that the steps can help prevent cognitive decline and dementia remains inconclusive.

“Even though clinical trials have not conclusively supported the three interventions discussed in our report, the evidence is strong enough to suggest the public should at least have access to these results to help inform their decisions about how they can invest their time and resources to maintain brain health with aging,” said Alan I. Leshner, chair of the academey committee that wrote the report and CEO emertus of the American Association for the Advancement of Science.

In the meantime, the study endorsed additional research on how to prevent cognitive decline and dementia. And Leshner noted that pursuing the three strategies would “do no harm.”

“At least two of them (blood pressure management and physical exercise) are really good for you” even if the brain link doesn’t pan out, he said.

Cummings, however, said the researchers set “an unreasonably high standard” in the study by demanding the type of gold-standard results produced by carefully controlled clinical trials.

“For example, everybody gets some exercise,” he said. “You can’t stop people from doing some exercise, so the data from a study isn’t as clear as with a drug trial. The same thing with food when it comes to blood pressure.”

Cummings has long argued that trials have shown that keeping the mind active through activities that include reading and language training can delay the onset of dementia. He notes studies have shown that the onset of Alzheimer’s comes three or four years later among multilingual individuals than those who know just one language.

What Cummings warns against, however, are the makers of computer games that promise “unrealistic results.”

“We can’t have people taken advantage of,” he said.

‘Sense of urgency’ lacking

He also said the U.S. government’s scientific national academy lacks a “sense of urgency” when it comes to Alzheimer’s disease.

“We have to raise consciousness. … The Academy has been too negative with the evidence on hand,” said Cummings, recognized by the Journal of Alzheimer’s Disease as one of the top international researchers of dementia.

Alzheimer’s disease is expected to affect close to 16 million Americans by 2050, about double today’s number.

The health care crisis worsens daily as 77 million baby boomers head into retirement.

Studies show that if present trends continue, Alzheimer’s will cost taxpayer-supported Medicare and Medicaid $20 trillion by 2050.

Earlier this week, the Ruvo Center released a study which found that the likelihood of reaching the national goal to develop a meaningful drug therapy for Alzheimer’s by 2025 is in jeopardy.

The study points out that while $6 billion in National Institutes of Health funds is spent yearly on basic research for cancer, just over a $1 billion a year in federal funding is spent on Alzheimer’s research. Cummings pointed out that while 5,000 anti-cancer drugs are being tested, only 100 drug trials are underway for Alzheimer’s.

According to the Alzheimer’s Association, one in nine people age 65 and older today has the disease, the age range of greatest risk of Alzheimer’s.

It projects that the number of people age 65 and older with Alzheimer’s will nearly triple by 2050, from today’s 5.2 million to a projected 14 million, barring a medical breakthrough.

Contact Paul Harasim at pharasim@reviewjournal.com or 702 387-5273. Follow @paulharasim on Twitter.

ad-high_impact_4
News
Thunder Mountain monument stands as a tribute to Native American culture
Caretaker Fred Lewis talks about Thunder Mountain monument in central Nevada, made from concrete and found items. The five-acre site is a tribute to Native Peoples of the West. (K.M. Cannon/Las Vegas Review-Journal)
New CCSD superintendent Jesus F. Jara aims for 1st in the nation
On his third day as Clark County School District superintendent, Jesus F. Jara talks about his vision for the future during a visit to Del Sol Academy of the Performing Arts on Thursday, June 21, 2018, in Las Vegas. (Marcus Villagran/Las Vegas Review-Journal) @brokejournalist
Ceremony Recognizes Refugee Students, Graduates
Rosy Mibulano, a graduate of Las Vegas High School who came to America from the Congo in 2015, was recognized in a ceremony for refugee students in Clark County. Like many other students relocated to Las Vegas from countries around the world, Rosy had a challenging high school experience, from learning English to adjusting to American customs and taking care of her family. On top of that, she wants to go to school to become a nurse so she can take care of her mother, who suffers from diabetes. The annual Refugee Recognition Ceremony celebrates the enormous lengths these young adults go through to create a new life for themselves. (Madelyn Reese/Las Vegas Review-Journal)
Paul McCartney is worth over $1 billion
Sir Paul McCartney is one of the most celebrated and accomplished musicians in history. He just turned 76 on June 18. McCartney grew to international fame with the Beatles and went on to become a wildly successful solo musician. Paul McCartney’s net worth is estimated at $1.2 billion, according to Celebrity Net Worth. In 2017, McCartney landed the No. 13 spot on Forbes’ list of the world’s highest-paid musicians, earning $54 million for the year. On Thursday, June 20, McCartney will release a double A-side single featuring two new songs, "I Don't Know" and "Come On to Me." McCartney has yet to announce a title of his new album or when it will be released. Th album is expected to be released before he headlines the Austin City Limits Music fest in October.
Water leak at Mandalay Bay convention center
The convention center area of Mandalay Bay in Las Vegas experienced major flooding Tuesday afternoon. Credit: Melinda Cook
Hollywood Memorabilia Up For Grabs at Las Vegas Auction
Elvis Presley's car, Marilyn Monroe's bras, Han Solo's blaster, and Jerry Lewis's "Nutty Professor" suit are just some of the items that are up for auction at Julien's Auctions at Planet Hollywood June 22 and 23. The auction's viewing room at Planet Hollywood is open to the public 11 a.m. to 6 p.m. daily through Saturday at Planet Hollywood. (Madelyn Reese/Las Vegas Review-Journal)
Indoor farming in Southern Nevada
Experts discuss Nevada's indoor farming industry. (Bailey Schulz/Las Vegas Review-Journal)
Former Fontainebleau could have become a Waldorf Astoria
Months after developer Steve Witkoff bought the Fontainebleau last summer, he unveiled plans to turn the mothballed hotel into a Marriott-managed resort called The Drew. But if Richard “Boz” Bosworth’s plans didn’t fall through, the north Las Vegas Strip tower could have become a Waldorf Astoria with several floors of timeshare units. (Eli Segall/Las Vegas Review-Journal)
New Springs Preserve Exhibit Shows Off "Nature's Ninjas"
"Nature's Ninjas" arrives at the Springs Preserve, in an exhibit and live show featuring critters that come with natural defenses, from armadillos to snakes, poison dart frogs to scorpions and tarantulas (Madelyn Reese/Las Vegas Review-Journal)
CrossRoads of Southern Nevada psychiatric urgent care to open in Las Vegas
Jeff Iverson, who operates the nonprofit sober living facility Freedom House, is opening a private addiction treatment center that will operate a detoxification center and transitional living for substance users trying to recover. (K.M. Cannon/Las Vegas Review-Journal)
Metro Capt. Jaime Prosser gives update of officer-involved shooting
Metro Capt. Jaime Prosser provides an update about an officer-involved shooting at Radwick Drive and Owens Avenue in the northeast Las Vegas on Thursday. A robbery suspect was shot and killed. (Bizuayehu Tesfaye/Las Vegas Review-Journal) @bizutesfaye
Wayne Newton surprises burglars
Wayne Newton and his wife, Kathleen, arrived at their southeast Las Vegas home shortly before midnight on Wednesday to find two burglars inside their house. The burglars fled and were seen heading north through the property. Las Vegas police quickly set up a perimeter and launched an extensive search of the area, but the suspects were able to escape. It was unclear if the burglars got away with anything of value. Several items, under the watchful eyes of the police, were seen on the ground near the home's main driveway. Neither Newton, nor his wife, were injured. The Newtons were not available for comment.
Police Officers Turn Off Body Cameras
In four separate body camera videos from the Route 91 Harvest festival shooting released Wednesday, officers in a strike team are instructed to turn their body cameras off and comply with the request.
Debra Saunders reports from Singapore
Las Vegas Review-Journal White House correspondent talks about the historic summit between President Donald Trump and North Korea's leader Kim Jong Un.
How long will North Korea's denuclearization take?
In Singapore, Las Vegas Review-Journal White House correspondent Debra Saunders asks President Donald Trump how long North Korea's denuclearization will take. White House video.
LVCVA purchase of gift cards hidden
A former LVCVA executive hid the purchase of $90,000 in Southwest Airlines gift cards in records at the agency. Brig Lawson, the senior director of business partnerships, said the money was for promotional events and did not disclose that it was for gift cards. Lawson also instructed Southwest employees to submit invoices without mentioning the purchases were for the cards. More than $50,000 of the cards cannot be accounted for. The convention authority is publicly funded . Lawson recently resigned.
Kim Jong Un visits Marina Bay Sands in Singapore
North Korean leader Kim Jong Un and his entourage visited the Marina Bay Sands in Singapore briefly Monday night, local time. (Video by Philip Chope)
Coca-Cola Bottle Purse Has 9,888 Diamonds
Designer Kathrine Baumann and jeweler Aaron Shum set the Guinness World Record for most diamonds (9,888) set on a handbag. The Coca Cola bottle-shaped purse was on display at the Coca Cola Store on the Strip. (Madelyn Reese/Las Vegas Review-Journal)
Sentosa Island a pleasure resort with a pirate past
The site of Tuesday's U.S.-North Korea summit is known for theme parks and resorts. But before that, it was known as a pirate island. (Debra Saunders/Las Vegas Review-Journal)
Judge Sandra Pomrenze's comment about girl's hair
Nevada Races Full of Women From Both Sides
It's already been a historic election season for women in politics. Record numbers of women are running for political office all over the country - including Nevada. (Madelyn Reese/ Las Vegas Review-Journal) @MadelynGReese
East Las Vegas home damaged by fire
Clark County Fire Department crews responded to a house fire in east Las Vegas Thursday morning. (Bizuayehu Tesfaye/Las Vegas Review-Journal) @bizutesfaye
911 call: Mom tries to get to son shot at Route 91
A woman stuck on the interstate during the Route 91 Harvest festival shooting on Oct. 1, 2017, in Las Vegas, tries to get to her son. 911 call released by Las Vegas police.
Las Vegas 911 caller reports people shot on Oct. 1
A 911 caller on Oct. 1, 2017, reports several people shot at the Route 91 Harvest festival in Las Vegas.
911 call from woman under stage in Las Vegas shooting
A 911 call from a woman underneath the stage at the Route 91 Harvest festival during the Oct. 1, 2017, Las Vegas shooting.
LVCVA facing scandal over gift cards
LVCVA is facing a growing scandal over airline gift cards. LVCVA bought $90,000 in Southwest Airline gift cards between 2012 and 2017. Now auditors can’t account for more than $50,000 of the cards. CEO Rossi Ralenkotter and his family used $16,207 in gift cards on 56 trips. Brig Lawson, the senior director of business partnerships, was responsible for buying and distributing the cards. He recently resigned.
Siblings separated in the foster care system get a day together
St. Jude's Ranch for Children and Cowabunga Bay Cares program partnered to bring 75 siblings together for the day to play on the water slides and in the pools at the Henderson water park. (K.M. Cannon/Las Vegas Review-Journal)
People flee the Route 91 Harvest festival on Oct. 1, 2017
Las Vegas police released footage from a camera on Mandalay Bay of the Route 91 Harvest festival on Oct. 1, 2017
Aaliyah Inghram awarded medal of courage
Aaliyah Inghram, a 10-year-old girl who was shot while protecting her 18-month-old brother and 4-year-old cousin during a shooting on May 8, awarded medal of courage. Bizuayehu Tesfaye/Las Vegas Review-Journal @bizutesfaye
Las Vegans Pack Public Lands Open House
A crowd filled the Clark County Library conference room Tuesday afternoon where Clark County officials hold their first -- and possibly only -- public meeting on plans to open almost 39,000 acres of federal land for development just outside the Las Vegas metropolitan area. County commissioners are set to vote June 19 on a potentially controversial resolution seeking federal legislation that would set aside tens of thousands of acres for conservation while giving Nevada’s largest community more room to grow. (Madelyn Reese/Las Vegas Review-Journal)
Local
Underground home was built as Cold War-era hideaway
The underground house at 3970 Spencer Street is one of the valley’s most unusual homes built 26 feet underground in 1978 by Girard “Jerry” B. Henderson, who, planned to survive the end of the world there.
Lip Smacking Foodie Tours takes you where the locals go
Donald Contursi talks about Lip Smacking Foodie Tours, which offers walking tours of restaurants on and off Las Vegas Boulevard with food samples and tidbits of history about the places they visit.
Bump stock manufacturers under fire
The Justice Department said last month that it had started the process to amend federal firearms regulations to clarify that federal law defines bump stocks as machine guns.
Art Bell’s Top 10 Shows
A selection of radio host Art Bell’s most popular shows.
Longtime Las Vegas attorney John Momot dies at age 74
Criminal defense attorney John Momot, who represented mob figures and even played himself in the movie “Casino,” has died.
David Copperfield in court after man injured during magic trick
The attorney for a British man who is suing illusionist David Copperfield said his client suffered serious injuries after being called on stage during Copperfield's show at MGM Grand.
5 things connecting Las Vegas and Marilyn Monroe
1. Marilyn Monroe, known then as Norma Jeane, obtained her first divorce in Las Vegas at the age of 20 on September 13, 1946. 2. According to some biographers, Monroe lived at 604 S. 3rd Street for four months during the summer of 1946. The house has since been torn down and is now the site of a parking lot. 3. In 1954, Monroe almost married Joe DiMaggio in Las Vegas but the wedding was called off last minute. The wedding was to be held at the Hotel El Rancho Vegas which was located on the southwest corner of Sahara Avenue and Las Vegas Boulevard. 4. Las Vegas has at least one road dedicated to the star. Marilyn Monroe Avenue is located in east Las Vegas and intersects with Betty Davis Street and Cary Grant Court. 5. There are currently more than 20 Marilyn Monroe impersonators for hire in the Las Vegas Valley.
Sir Richard Branson announces purchase of Hard Rock Hotel
Sir Richard Branson, founder of the Virgin Group, has acquired the Hard Rock Hotel with partners and plans to turn it into a Virgin-branded property by the end of 2019.
3 Centennial High School students killed in Calif. crash (Full)
Three Centennial High School students were killed Thursday morning in Southern California when their vehicle was struck by a suspected drunken driver while they were enjoying their spring break, according to a family member of one of the victims.
Retail Restroom Sexual Assault Suspect
Las Vegas police are asking for help finding a man they said groped a woman in a south Las Vegas Valley restroom. (Las Vegas Metropolitan Police Department)
Calvary Christian Learning Academy, “There was no fair warning.”
Samantha O’Brien, whose three-year-old daughter attended the Calvary Christian Learning Academy daycare, found out Monday night when her daughter’s teacher called about the school closing.
Life
Bark-Andre Furry meets Capitals superfan Ovie the Bulldog
Two of NHL's furriest fans met at the Forum Shops in Caesars Palace on Tuesday, June 18, 2018, in Las Vegas. Vegas Golden Knights superfan Bark-Andre Furry and Washington Capitals superfan Ovie the Bulldog shared a plate of meatballs and spaghetti with help from Logan, "The Girl with the Hat." (Marcus Villagran/Las Vegas Review-Journal) @brokejournalist
Art Bell’s Top 10 Shows
A selection of radio host Art Bell’s most popular shows.
Calvary Christian Learning Academy, “There was no fair warning.”
Samantha O’Brien, whose three-year-old daughter attended the Calvary Christian Learning Academy daycare, found out Monday night when her daughter’s teacher called about the school closing.
TOP NEWS
News Headlines
ad-infeed_1
ads_infeed_2
Local Spotlight
Home Front Page Footer Listing
Circular
You May Like

You May Like