Patrick Mahomes is the clear +350 favorite at the Westgate to win his second NFL MVP award, and the Chiefs are the +450 favorites to repeat as Super Bowl champions.
NFL betting preview
Lamar Jackson earned NFL MVP honors and led Baltimore to a 14-2 record, but he needs a postseason victory to finally silence his doubters.
San Francisco was a few minutes away from beating the Kansas City Chiefs. Now it has to start the journey over, this time with a target on its back.
New Orleans went 6-1 last season in games decided by seven points or less. But handicapper Scott Kellen expects that record to regress and the Saints to go under 10½ wins.
The Cowboys’ win total of 10 is the best in the NFC East, and they’re a -175 favorite to win the division under first-year coach Mike McCarthy.
The Eagles hope they can become the first team to repeat as NFC East champion since they won four straight from 2001-04.
Pittsburgh had terrible quarterback play after Ben Roethlisberger’s season-ending injury, and his return probably will put the team back in the playoff mix.
Seattle has made the playoffs in seven of the quarterback’s eight seasons, but it has not advanced past the divisional round since 2014.
The Colts were a playoff team without a playoff-caliber quarterback last season. Now they’re betting on Philip Rivers to fill that role and show he has something left at age 38.
At least one bettor at the Westgate is a big believer in the Bills. The gambler on Thursday placed a $3,350 wager to win $100,500 on Buffalo to win the Super Bowl (30-1).
The Vikings are hoping for more consistent play from Kirk Cousins and a strong defense to claim the title in a competitive NFC North.
The Green Bay Packers went 13-3 and reached the NFC championship game last season, but their season win total of nine is being shaded toward the under.
New England has won at least 10 games in an NFL-record 17 straight seasons and claimed 11 AFC East titles in a row. But both streaks appear to be in jeopardy.
Cleveland was an overhyped dud last season, going 6-10. First-year coach Kevin Stefanski will try to get quarterback Baker Mayfield back on track.
Tennessee made a playoff run with a solid defense and bruising running back Derrick Henry. Now it has to prove that style is replicable.