Oakland, still in the playoff hunt, is perhaps at its lowest point following lopsided losses at Kansas City (40-9) and the New York Jets (34-3).
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The Chiefs are 8-2 in their past 10 games as underdogs. New England is 16-5 ATS in its last 21 home games.
In 14 December games, Tennessee Titans running back Derrick Henry has carried 225 times for 1,176 yards and 14 touchdowns. He ran for 149 yards last week at Indianapolis.