Oscar De La Hoya, 48, who has not fought since he retired on his stool against Manny Pacquiao at MGM Grand in 2008. Vitor Belfort is a former UFC champion who won his only bout as a professional boxer.
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Mayer (14-0, 5 KOs) will take on former two-division titlist Erica Farias (26-4, 10 KOs) Saturday in the co-main event of a Top Rank card from Virgin Hotels Las Vegas.
Leo will fight Aaron Alameda on the undercard of Jermall Charlo-Juan Macias Montiel WBC middleweight world title fight.
This was Whittaker’s third straight win, all coming against elite competition.