The Los Angeles Lakers (27-31), the +350 second choice to win the NBA title in the preseason, soared to 50-1 on Wednesday, their longest odds of the season.
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The Illini opened as high as 100-1 and were 25-1 for much of the season, but are now the second betting choice behind Gonzaga.
Bettors and bookmakers will have to compete to keep up with news on about 350 Division I teams during the season that starts Nov. 25.
Professional bettor Erin Rynning likes Damian Lillard and the Portland Trail Blazers to continue their hot streak in Game 1 against the Los Angeles Lakers on Tuesday.
Las Vegas, which lost in the semifinals last season, leads a clear division between the top six teams in the league and the bottom six.
A Westgate bettor placed a $100,500 wager to win $2,010 on the 76ers to make the playoffs and $10,000 to win $100 on the Bucks to make the playoffs.
The Westgate and William Hill sportsbooks had six figures of liability on Tiger Woods and Phil Mickelson, and neither golfer threatened.
The Ducks — fresh off their Pac-12 conference tournament title run at T-Mobile Arena — quickly moved to 1-point favorites Sunday night over No. 5 seed Wisconsin after opening as 1½-point underdogs.
Derek Stevens, who owns the D Las Vegas and Golden Gate, placed a $100,000 bet to win $105,000 on an intriguing college basketball prop at the South Point sports book.
A ruling by the Supreme Court this week caused the NCAA to act swiftly by removing its outdated blinders in regard to staging championship competition in states that offer sports gaming.