Underdogs went 9-3 ATS with seven outright wins, including upsets by the Jaguars (+16) over the Bills and Broncos (+10) over the Cowboys.
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The Los Angeles Chargers opened as 3-point favorites and were bet to -3½ after Right Angle Sports, a respected handicapping service, released a play on the Chargers -3.
Despite being tied for first place with the unbeaten Denver Broncos (3-0), the Raiders remain +550 long shots at BetMGM to win the division after opening the season at 18-1.
The Raiders are arguably the most surprising 2-0 team after traveling across the country on a short week and beating the Steelers 26-17 on Sunday as 5½-point underdogs.
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The Chiefs have reeled off three consecutive 12-win seasons, and Las Vegas oddsmakers expect them to hit that mark again in the first 17-game regular season in NFL history.
Las Vegas sportsbooks make adjustments for the coronavirus but still attract plenty of action on pro football’s opening Sunday.
The Patriots ascended from the 6-1 second choice, behind the Chiefs, to the 4-1 favorites at the Westgate sportsbook.
Denver dropped to a 1-point favorite at most Las Vegas sportsbooks Friday after Raiders coach Jon Gruden said the plan is for Brown to play against the Broncos.