A 71-year-old man was killed in Henderson, another man was killed in Summerlin, and a 29-year-old pedestrian was struck and critically injured in northeast Las Vegas.
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About 50,000 people were expected at Lake Mead, which is outside Las Vegas, over this Memorial Day weekend.
Another day, another miles-long backup of traffic on Interstate 15 heading south out of Las Vegas, officials said.
Nomi Armendariz, 16, was last seen on Saturday morning in the northwest Las Vegas Valley.
Keven Galan died Sunday morning, almost two months after the Aug. 2 crash on East Washington Avenue west of North Pecos Road.
Officials have identified the man shot dead Monday by a Henderson police officer. The officer also has been identified.