Las Vegas police said a man was riding a motorcycle on South Maryland Parkway when he struck a curb and was ejected from the bike.
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The incident included three vehicles at East Warm Springs and South Pecos Road.
The annual Rock ‘N’ Roll Running Series returns to Las Vegas this weekend, meaning motorists should expect traffic impacts on the Strip and downtown.
The driver of the truck stayed at the scene and impairment is not suspected, police said. The woman was pronounced deceased at the scene.
When the Tropicana Avenue bridge over Interstate 15 reopens, a diverging diamond interchange lane system will again be in place.
The collision occurred abut 9:30 p.m. at West Charleston and Decatur boulevards, police said.
The next major phase of the multiyear Interstate 15-Tropicana Avenue project includes a full Interstate 15 closure.
Heavy traffic affected the valley as Super Bowl visitors departed Las Vegas.
Impairment is suspected in a 4:12 a.m. Saturday crash at North Lamb Boulevard and East Bonanza Road, according to Metropolitan Police Department Lt. Matt Arnold.
A pedestrian was struck and killed by an SUV in south Las Vegas Friday evening.