A Toyota minivan and a Yamaha collided at about 10:48 a.m. near South Eastern and East Wigwam Avenue, according to a Metropolitan Police Department release.
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More traffic disruptions are scheduled for Interstate 15 near Tropicana Avenue.
This weekend, drivers in downtown Las Vegas may be affected by closures on Las Vegas Boulevard.
Heavy snow closed several of the major roads leading to and from Las Vegas for parts of the day on Wednesday.
A stretch of Interstate 15, one of the most traveled roads in Nevada, is closed in the central valley all weekend.
A man was fatally struck by a vehicle that drove off Wednesday night in southeast Las Vegas.
Another day, another miles-long backup of traffic on Interstate 15 heading south out of Las Vegas, officials said.
The average price of regular unleaded gasoline in Las Vegas surpassed the $4 per gallon mark over the weekend.
A portion of the 215 Beltway was closed in the Summerlin area Friday after Las Vegas police stopped a wrong-way driver, according to police and a witness.
Traffic was backed up as much as 20 miles on the way out of Las Vegas to California on Sunday morning, according to a tweet from the Regional Transportation Commission.